Advanced Labs Pte. Ltd.

RAPTOR 4.2: Protein Structure Prediction Software

robert — Fri, 07 Nov 2008 11:12:37 +0000

Waterloo, Canada - Nov. 6, 2008…Bioinformatics Solutions Inc. has announced the release of RAPTOR 4.2, a protein threading software package, ranked as one of the very top servers in CASP8 (Critical Assessment of Techniques for Protein Structure Prediction 2008) for all targets, for the fourth consecutive competition.

RAPTOR accurately predicts protein structures by threading a query protein sequence through structure template libraries. The latest edition of RAPTOR, version 4.2, offers a new internal 3D structure modeling application to eliminate the need for expensive third-party Modelling software. Further RAPTOR applications include three different threading engines and a homology search module (PSI-BLAST based).

CASP is a community-wide competition to advance the field of protein structure prediction taking place every two years since 1994. Ranking for this competition is based on more than 80 protein structure prediction servers worldwide. Protein structures that are either expected to be solved shortly or that have been recently solved, yet to be released to the public are used as targets for the prediction. Each server’s performance is measured by the sum of its prediction quality scores for all targets. Several assessment groups perform independent rankings. According to the ranking list generated by TM-score, RAPTOR is placed 2nd among all the servers. The well-known ROBETTA server is ranked number 5 in the same list.

RAPTOR first appeared in CAFASP3 (CASP5) in 2002 and was ranked number one in the individual server group for that year. Since then, RAPTOR has actively participated in every CASP and received consistently top rankings. The RAPTOR software package is provided by Bioinformatics Solutions Inc.

More information about RAPTOR including a 30-day evaluation license, please contact Advanced Labs.

iCHEMS - Chemical Inventory Tracking for Laboratories

robert — Wed, 06 Feb 2008 02:31:03 +0000

Singapore - Feb. 6, 2008…Chemical inventory management has been somewhat neglected by software developers because chemical stockrooms are not regulated by Government agencies even in pharmaceutical companies. The rise in cost of chemicals and reagents as well as the trend towards a paperless office require that laboratory personnel track inventory electronically.

iCHEMS integrates a robust chemical information database management system with a front-end interface focusing on the cabinet. The highlight of the software is that it tracks the usage of chemicals robustly. Similar to the way library books are checked-in and checked-out, the system not only captures, creates, and stores information of any new or existing laboratory chemicals, but also it executes and maintains it in a real-time and consistent manner.

iCHEMS reduces the hassle of manual inventory management in hard copies, saving time, space and effort and thereby increase the efficiency of the entire laboratory. In addition, the system stores all audit history and is CFR 21 Part 11 compliant. It is designed for use by universities, Government agencies, and private research laboratories.

iCHEMS was developed by our partner KOOPrime Pte Ltd. Please contact Advanced Labs for more information.

Lambert Instruments exhibiting at BiOS 2008 and SPIE Photonics West

robert — Fri, 18 Jan 2008 23:44:22 +0000

Leutingewolde, The Netherlands - Jan. 18, 2008…SPIE Photonic West is the only photonics event in North America covering the entire spectrum of light-driven technologies.

BiOS 2008 (part of SPIE Photonic West) is the world’s largest and most prestigious international biomedical optics and imaging conference. The BiOS exhibition provides the ideal venue for interacting with the early adopters of the newest biomedical technologies, as well as a launch pad for new applications and technologies in diagnostics, therapeutics, and instrumentation. For companies involved in biomedical optics, BiOS is the place to see and be seen.

Biomedical Optics Exhibition: January 19-20, 2008
Photonics West Exhibition: January 22-24, 2008

At the SPIE Photonic West, Lambert Instruments can be found at the “Holland Pavilion” that is organized by the Photonic Cluster Netherlands. At both events Lambert Instruments will be featuring their widefield FLIM products, as well as other products making use of image intensifiers like intensified high-speed camera’s.

If you are at the event, make sure to stop by the Lambert Instruments booth.

Booth Details

BiOS: #8319 (shared booth with ISS, Lambert’s USA distributor)

SPIE Photonics West: #6278, South Hall 1

Contact Advanced Labs for more information about Lambert Instruments products.

PEAKS Studio Promotion - 10% off until Year-end

robert — Mon, 03 Sep 2007 13:55:59 +0000

Singapore - Sept. 3, 2007…PEAKS Studio, de novo sequencing and protein ID software, is even more affordable with our year-end special pricing.

Corporate customers and government institutes will receive 10% off the retail price of BSI’s PEAKS Studio 4.5 software for de novo sequencing and protein/peptide identification. Academic customers will receive 5% off their already discounted low price*. To qualify, orders must be received before December 31, 2007.

Read more and download the brochure here.

*Offer valid only in the following countries: Singapore, Malaysia, Thailand, China/Hong Kong/Taiwan, Korea, India and Viet Nam.

PEAKS Studio 4.5 - De Novo Sequencing Software

robert — Tue, 10 Jul 2007 13:25:10 +0000

Waterloo, Canada - July 10, 2007…BSI (Bioinformatics Solutions Inc.) announced today, their much anticipated release of PEAKS 4.5 for peptide mass spectrometry analysis. PEAKS, known for its leadership role in de novo sequencing (sequencing of peptides not present in any database) is once again guiding tandem mass spectrometry researchers into in a new era of data analysis through sequence reconstruction. Accurate sequence reconstruction is performed by the built in SPIDER tool, which has been demonstrated to increase peptide findings by upwards of approximately 20%.

Other cutting-edge enhancements to PEAKS help researchers to identify peptides using predicted retention time. PEAKS provides all of the necessary tools for superior peptide sequence derivation and protein identification from tandem MS/MS spectra - all within an intuitive graphical interface. PEAKS Studio 4.5 provides fast, accurate results for spectra from both sequenced and unsequenced organisms. Instrument Capabilities: Researchers are now fully capable of processing raw data, straight from their instruments (Agilent, Bruker, Shimadzu, Thermo and Waters to name a few).

Here is what BSI has bundled into PEAKS 4.5:

10% - 30% improvement in de novo sequencing accuracy on ion-trap data.
Improvements to the inChorus search engine:
- Better integration with Sequest and Mascot - searches can be launched from inChorus, and/or existing results imported.
- Existing results from any search engine can be loaded in (including PEAKS), avoiding having to repeat the search.
- A separate local database is defined for recompiling the results based on peptides from all search engines.
- The new RSD metric is available for all results, regardless of search engine.
Improvements to instrument flexibility
- Any combination of mass analyzer, fragmentation (incl. ETD) and ion source can be custom configured.
- For ease of use, PEAKS will automatically check the data to detect the scan mode.
A new, revolutionary tool in SPIDER allows you to not only find homologous peptides, but also reconstruct the real sequence, confirming mutation and correcting de novo sequencing errors.
Retention time prediction: an RT is predicted for each peptide, and you can filter search results by (realRT – predictedRT).
Data quality score now available, allowing a second evaluation of sequencing results trustworthyness.
All parameters (start to finish) plus user’s notes included on result export.
Improved charge and mono-isotopic peak picking mean even better coverage.
Spectra can be exported to SVG, a standard graphics format, so you can move and resize parts of the picture.

Please contact Advanced Labs for a demo or a quotation.

Tags: peptides, protein, sequencing

Clarinox Technologies Introduces ClarinoxEdel Smart Sensor System

robert — Mon, 18 Jun 2007 13:15:59 +0000

Melbourne, Australia - June 18, 2007…Clarinox Technologies Pty Ltd, home of wireless and embedded systems solutions, in collaboration with Edel Mikroelektronik announces the ClarinoxEdel Smart Sensor range of products.

The ClarinoxEdel Smart Sensor System is a low-power sensor system comprised of smart tags, smart readers, and smart software. The system can be used to measure, log and store parameters such as environmental temperature or humidity. As tags are active they can also form part of an on/off control system. Applications range from intelligent inventory, depot management, agricultural applications, industrial climatic monitoring to item and asset tracking the ClarinoxEdel Smart Sensor System makes life easier for developers.

The ClarinoxEdel range complements Clarinox’s philosophy of providing designers the ability to readily add technologies to their designs - now BluetoothTM , RFID, and the ClarinoxEdel technologies can easily be added. Modern complex electronic device designs require the selection of the most appropriate hardware, RTOS, middleware, drivers and protocols to combine neatly to provide the best base for the application layer development. This task can be quite complex and often needs to be completely redone for the next design. Middleware from Clarinox Technologies allows much greater reuse of application layer for the next project and allows greater flexibility to change target within the design cycle should design criteria change. This results in large savings for companies developing complex wireless electronics.

About Clarinox Technologies Pty Ltd

Based in Melbourne, Australia, Clarinox provides wireless and embedded systems solutions, including both digital hardware design and software development, with expertise covering many processors and real time operating systems, Bluetooth™ Protocol Stacks with Simplest Ever API (C++/C), Device Driver Development and Porting Services. Visit Clarinox Technologies at CommunicAsia 2007 (Booth 3J1-03).

Download PDF

Please contact Advanced Labs for more information.

Tags: wireless

PEAKS at ASMS 2007

robert — Fri, 08 Jun 2007 12:56:50 +0000

Waterloo, Canada - June 8, 2007…Bioinformatics Solutions Inc. (BSI) has completed another successful ASMS Conference. Two new tools introduced were the new SPIDER, which leads to better understanding of proteins by finding mutated peptides, and inChorus, that lets you directly launch multiple search engines (including Sequest and Mascot) to get better results.

Other improvements allow you to better organize your findings, export results. In short, you can easily integrate de novo sequencing with your other tools — that’s important because you’ll never get better confirmation of peptide hits, and you’ll pick up new peptides that couldn’t be found any other way.

Posters Presented

Reconstruction of peptide sequences from de novo sequences and their homologes
Improving de novo sequencing accuracy for ion trap data in PEAKS software
Improving sequence coverage by de novo sequence homology searching with SPIDER
Optimizing data acquisition for automated de novo sequencing of peptides
Automated identification of disulfide-bonded dipeptides using PEAKS and Q-TOF mass spectrometry

You can download the User’s Pack. It contains all the information from the posters that BSI exhibited at the conference.

If you are located in Asia-Pacific, contact Advanced Labs for more information, a PEAKS demo, or a quotation. We promise the lowest prices.

Tags: ASMS, sequencing

Clarinox Technologies and Advanced Labs at CommunicAsia 2007

robert — Sun, 13 May 2007 23:59:09 +0000

Singapore, Singapore - May 14, 2007…Clarinox Technologies Pty Ltd together with Advanced Labs Pte Ltd will exhibit at CommunicAsia 2007 (June 19-22 at Singapore EXPO). You can find us at Booth #3J1-03 within the Australian National Pavilion.

Clarinox simplifies complex electronic device designs. The ClarinoxTMBlue V2.0 + EDR Bluetooth protocol is now available for an even larger range of target platforms. Designers can now easily add Bluetooth technology to their designs and have the flexibility to use their applications on other platforms.

“Modern complex electronic device designs require the selection of the most appropriate hardware, RTOS, middleware, drivers and protocols to combine neatly to provide the best base for the application layer development. This task can be quite complex and often needs to be completely redone for the next design.” Says Gokhan Tanyeri, CTO, Clarinox Technologies, “the middleware from Clarinox Technologies allows much greater reuse of application layer for the next project and allows greater flexibility to change target within the design cycle should design criteria change. This results is large savings for companies developing complex wireless electronics.”

We are Interesting in Meeting

- Systems Integrators
- Device developers
- Potential distributors or alliance partners
- Those seeking an Australian/Singapore resellers

About Bluetooth^TM

Bluetooth is a short-wave radio frequency based technology that allows devices to communicate without wires over short-range networks. The distinguishing characteristics of Bluetooth^TM technology are small footprint, low cost, low power consumption and secure, robust communications. Bluetooth^TM and the Bluetooth^TM logos are trademarks owned by Bluetooth SIG, Inc., USA.

About ClarinoxBlue^TM

The ClarinoxBlue protocol is available for many embedded targets including Texas Instruments DSP-BIOS; eCos; QNX Neutrino; GreenHills Velosity; uClinux; WindowsCE/.net - and for flexibility and ease of development in a desktop environment Windows; Linux; and Cygwin are all supported environments. Further targets are constantly being added so for more up to date information please inquire.

About Clarinox Technologies Pty Ltd

Based in Melbourne, Australia, Clarinox Technologies provides Embedded Systems and Short Range Wireless solutions. Resolving the major issues confronting the embedded business community is the driving force for our middleware software and hardware reference design product development. The middleware software products, ClarinoxTMSoftFrame, ClarinoxTMBlue and ClarinoxTMScan, combined with Clarinox hardware reference designs for Bluetooth, RFID, and other technologies, produce a quick and efficient means to develop a wireless embedded device. Visit www.clarinox.com

About Advanced Labs Pte Ltd

Advanced Labs is the authorized reseller and local point of contact for all inquiries regarding Clarinox Technologies products in the Southeast Asia.

Reference Links

CommunicAsia 2007 - General Information
CommunicAsia Clarinox Press Release
Clarinox Exhibitor Listing
Contact Advanced Labs

Tags: Bluetooth, RFID

Lambert Instruments Announces New Gated Intensified High-Speed Camera

robert — Tue, 17 Apr 2007 03:48:38 +0000

Leutingewolde, The Netherlands - April 16, 2007…Lambert Instruments has extended the range of it’s high-speed camera product line with the “new” HI-CAM CR, gated intensified high-speed camera.

The HI-CAM CR records images up to 100,000 fps allowing recording of fast events at high time-resolution. At the same time, the HI-CAM CR offers single photon detection capability. Fast moving objects are recorded sharply by shuttering the image intensifier down to 40ns and optionally 5ns.

The dual stage image intensifier is specially designed for the use in high-speed cameras. (Photocathodes with different spectral response from the UV to the near IR are available). Enhanced maximum output brightness results in a optimal signal/noise ratio at high frame rates. The intensifier is coupled to the CMOS sensor by using tapered fiber optics that matches the intensifier to the sensor format.

Main Features

2-stage image intensifier
100,000 fps max. recording rate
Up to 8GB internal memory
Minimum exposure 40ns, optional 5ns
Sensitivity 0.0001 lx
C-mount input or F-mount
Software for camera/intensifier control, image viewing and storage

Applications include

Combustion research
Time Resolved Fluorescence
Industrial Testing
Particle Image Velocimetry
Process trouble shooting
Ballistics

Download Movie: Blue gas flames at 1000fps

Download Movie: Blue gas flames at 4000fps

Contact Advanced Labs for more information or a quotation.

Tags: high-speed camera

RAPTOR 4.1 - Protein Threading Software

robert — Mon, 26 Mar 2007 22:38:46 +0000

Waterloo, Canada - March 26, 2007…Bioinformatics Solutions Inc. (BSI) has announced the release of RAPTOR 4.1 for Linux and Windows, the latest edition of protein threading software. RAPTOR is an innovative software tool designed to predict protein structure from protein sequence. Armed with unique integer programming algorithm, RAPTOR is capable of discovering remote structural homology for hard sequences and giving high quality prediction.

As a participant in recent CASP’s, RAPTOR has been consistently ranked in the top tier. In addition to the three threading methods proprietary to RAPTOR, the new version integrates PSI-BLAST for rapid identification of easy targets. A built-in pipeline in RAPTOR 4.1 allows users to automatically run more rigorous threading techniques if necessary. RAPTOR 4.1 is your protein structure pipeline, right out of the box.

See the new Raptor GUI.

If you are located in Asia-Pacific, contact Advanced Labs for more information, a demo, or a quotation. We promise the lowest prices.

Tags: protein structure, proteomics