Confocal Lifetime Images on a Widefield Fluorescence Microscope

Leutingewolde, The Netherlands - Nov. 21, 2006…Lambert Instruments announced today the capabiltiy to obtain confocal lifetime images on a widefield fluorescence microscope using the Lambert LIFA System.

The Lambert LIFA is used together with a fluorescence widefield microscope and a CSU10 spinning disk from Perkin Elmer/Yokogawa. The intensified CCD camera of the LIFA is used as detector by mounting it on the camera port of the CSU10 spinning disk. In this set-up, the light source is not the modulated LED typically used, but instead a modulated 470nm laser diode (PicoQuant). The rest of the set-up uses the standard LIFA components.

Tags: fluorescence, widefield microscope

Lambert FLIM Software Update

Leutingewolde, The Netherlands - Nov. 15, 2006…Lambert Instruments announced today that the FLIM (Fluorescence Lifetime Imaging Microscopy) software available with their LIFA (Lambert Instruments Fluorescence Attachment) has been improved with a number of added features:

Acquisition
• Single frequency measurements.
• Time series: can be triggered from the camera to the control box.
• Multi-frequency measurements: analysis of multiple lifetime components per pixel or ROI.

Analysis
• Profile plot: to observe the lifetime values per line (x or y) of the image.
• Fit-on-point: to check the reliability of the acquisition per pixel.
• Statistics: to analyze the lifetime image per ROI in values/histograms.
• Polar plot: to analyze phase/modulation data of all pixels in one curve.
• Freeform: ROI can be drawn and is moveable through the images.
• Merge: lifetime and intensity images to get better insight of the data in images.

Tags: Fluorescence

ClarinoxScan Middleware Incorporates UHF

Melbourne, Australia - October 23, 2006 …Clarinox Technologies Pty. Ltd., home of wireless and embedded systems solutions, expands the capability of its ClarinoxScan middleware to incorporate UHF and HF RFID frequencies. “This is a significant development,” states Gokhan Tanyeri, CTO of Clarinox Technologies, “as now we can readily cater for complex systems in which either UHF or HF frequencies are used, or even a mixture of both. Classes of devices can be set to incorporate data captured by either frequency”.

Tags: UHF, RFID

New Lambert Intensified CCD Day/Night Camera

Leutingewolde, The Netherlands - Oct. 19, 2006…Lambert Instruments announced today the introduction of a new auto-gating surveillance ICCD camera featuring the highest sensitivity and resolution. The new camera incorporates a Photonis-DEP XR-5 Image Intensifier.

An Intensified CCD (ICCD) camera is an electronic camera, analogue or digital, equipped with an intensified CCD as image sensor. The sensor uses an image intensifier that is fiber optically coupled to the CCD chip to increase the sensitivity down to single photon level. An ICCD camera allows image acquisition at very low light levels over a wide range of spectral response and at relatively high speed. Single photons can be detected and discriminated from CCD noise. Ultra high-speed phenomena can be captured by using the intensifier as a fast shutter (gating).

Tags: ICCD, camera, CCD

PEAKS Studio Promotion - 10% off until Year-end

Singapore - Sept. 18, 2006…Corporate customers and government institutes will receive 10% off the retail price of BSI’s PEAKS Studio 4.0 software for protein and peptide identification. Academic customers will receive 5% off their already discounted low price*. To qualify, orders must be received before December 31, 2006.

Read more and download the brochure here.

Contact us for a quotation.

*Offer valid only in the following countries: Singapore, Malaysia, Thailand, China/Hong Kong/Taiwan, Korea, India and Viet Nam.

RAPTOR 4.0 - Protein Threading Software

Waterloo, Canada - Sept. 6, 2006…Bioinformatics Solutions Inc. (BSI) has announced the release of RAPTOR 4.0 for Linux, the latest edition of protein threading software. RAPTOR is an innovative software tool designed to predict protein structure from protein sequence. Armed with unique integer programming algorithms, RAPTOR is capable of discovering remote structural homology for hard sequences and giving high quality prediction.

White-light TIRF combined with FLIM

Leutingewolde, The Netherlands - August 10, 2006…Lambert Instrument news. TIRF (Total Internal Reflection Fluorescence) microscopy facilitates extremely high-sensitivity and high-contrast visualisation of small spots near the cover glass, without disturbing cellular activity, thereby enabling the tracking of biomolecules, and the study of their dynamic activity and interactions at the molecular level. This new combination of TIRF and frequency domain FLIM makes it possible to measure lifetimes of small adhesion points near the cover glass.

Tags: microscopy, TIRF, FLIM

PEAKS Studio 4.0 - De Novo Sequencing Software

Waterloo, Canada - June 30, 2006…Bioinformatics Solutions Inc. (BSI) is proud to announce the release of the much anticipated Version 4.0 of PEAKS Studio. The latest in de novo sequencing and protein identification software yielding fast and accurate results from tandem mass spectrometry (MS/MS) data.

By automatically filtering out insufficient quality results before database searching users can get the most out of low resolution data. Further, an increase in coverage is obtained by using four search engines for protein identification, instead of just one.

Tags: mass spectrometry